发明名称 NOVEL BISPHOSPHONATES
摘要 PCT No. PCT/DK89/00071 Sec. 371 Date Oct. 9, 1990 Sec. 102(e) Date Oct. 9, 1990 PCT Filed Mar. 29, 1989 PCT Pub. No. WO89/09775 PCT Pub. Date Oct. 19, 1989.The present invention relates to compounds of formula in which R1-R8 can be the same or different and stand for hydrogen or a straight or branched aliphatic C1-C10 hydrocarbon radical. In addition, R3 when taken together with either R1 or R5 can form a saturated aliphatic 5-, 6-or 7-membered ring, which may be substituted with one or more C1-C4-alkyl radicals. The present compounds are effective e.g. in drugs influencing calcium metabolism.
申请公布号 ZA8902465(B) 申请公布日期 1989.12.27
申请号 ZA19890002465 申请日期 1989.04.04
申请人 LEO PHARMACEUTICAL PRODUCTS LTD A/S 发明人 ERNST TORNDAL BINDERUP;SVEN LIISBERG
分类号 A61K31/675;A61P43/00;C07F9/572 主分类号 A61K31/675
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