摘要 |
PURPOSE:To obtain a melanization inhibitory drug for external use, containing glabridin as an active ingredient, having excellent inhibitory action on tyrosinase activity and useful for preventing skin blackening, liver-spot and ephelis from occurring. CONSTITUTION:The objective substance obtained by containing 0.0007-0.05% light yellow glabridin or colorless glabrene as an active ingredient and preparing a pharmaceutical by a conventional method. The drug is used by preparing in the form of cosmetic, ointment, lotion, liniment or emulsion. The glabridin and glabrene are extracted from roots of licorice and effective in a small amount without side effects, chemically stable and capable of being freely blended with various cosmetics, drugs for external use, etc. |