| 摘要 |
PURPOSE: To obtain a medical composition suppressing T cell function independently of lipoxygenase inhibition by including a specific 3-substituted-2- oxyindole-1-carboxyamide. CONSTITUTION: This medical composition contains a compound expressed by the formula (X is H, Cl, F; Y is H, Cl; R is benzyl, thienyl) or its pharmaceutically permissible basic salt. This composition is useful for treatment of systemic autoimmune disease of a mammal mediated by T cell (for example; multiple sclerosis, systemic lupus erythematosus) and organ-specific autoimmunity inhibition (for example; type I diabetes, paralytic amyosthenia, chronic hepatitis).
|
