摘要 |
<p>Compounds of formula (I) or salts thereof: <CHEM> wherein: each R1 is independently hydrogen or a silyl protecting group; R2 is a carboxylic acid or derivative thereof; a ketone or aldehyde function; hydroxymethyl in which the hydroxyl function is optionally silylated, or substituted by hydroxy C1-4 alkyl, alkoxy C1-4 alkyl, alkoxycarbonyl C1-4 alkyl, hydroxycarbonyl C1-4 alkyl, alkyl, alkanoyl, or optionally substituted aryl or arcyl; one of X and Y is hydrogen, and the other is a sugar residue; hydroxy; optionally substituted C1-6 alkoxy or C3-8 cycloalkoxy, alkanoyloxy; thioalkanoyloxy; sulphonyloxy; halogen; or optionally substituted aryloxy, aralkyloxy or aroyloxy; or X and Y together with the carbon atom to which they are bonded are a carbonyl group or derivative thereof, are provided; their use as chemical intermediates and in the treatment of fungal infections is described.</p> |