Procédé de préparation d'un vaccin

摘要

A vaccine for combating Salmonella dublin infection in calves comprises the strain of Salmonella dublin having the A.T.C.C. deposit number 15480 and a pharmaceutically acceptable diluent. The vaccine is preferably in the form of an injectable composition and may be formulated using freeze-dried organisms. The organisms may be harvested from an ordinary culture and re-suspended in conventional diluents or a broth culture of the organisms may be used as the vaccine. Useful degrees of immunity against Salmonella dublin infection in calves are also obtained by vaccines comprising a live attenuated strain of Salmonella gallinarum, and a mixed vaccine containing the above Salmonella dublin vaccine and Salmonella gallinarum vaccine. The Salmonella dublin vaccine may be used as a prophylactic measure against related Salmonella infections, e.g. Salmonella typhimurium infections.