发明名称 4-Amino-3-carboxynaphthyridine derivatives, their preparation and pharmaceutical compositions.
摘要 <p>The compounds according to the invention correspond to the formula &lt;IMAGE&gt; in which R1 and R2 independently of each other denote the hydrogen atom, a C1-C6 alkyl group, a phenyl or benzyl group, or R1 and R2 with the nitrogen atom to which they are attached may form a saturated C4-C8 heterocyclic ring, R3 and R4 independently of each other denote the hydrogen atom or a C1-C6 alkyl group, R5 denotes a hydrogen or halogen atom or a C1-C4 alkyl, C1-C4 alkoxy, nitro or trifluoromethyl group, n is 1,2 or 3, and one of the symbols A, B, C and D denotes N and the others denote CH, and the N-oxides and their addition salts with phamaceutically acceptable acids and bases. &lt;??&gt;Medications. </p>
申请公布号 EP0346207(A1) 申请公布日期 1989.12.13
申请号 EP19890401547 申请日期 1989.06.05
申请人 SANOFI 发明人 MENDES, ETIENNE;VERNIERES, JEAN-CLAUDE;SIMIAND, JACQUES, EDOUARD;KEANE, PETER EUGENE
分类号 A61P25/20;A61K31/435;A61P9/08;A61P9/10;A61P37/00;C07D471/04 主分类号 A61P25/20
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