发明名称 |
Anticoagulant therapy |
摘要 |
A composition and method for treating thrombotic disorders. The composition comprises a peptide comprising an amino acid sequence corresponding to the sequence of the amino acid residues in the EGF domain of Factor IX, or a subsequence thereof. Such peptides compete with coagulation Factors IX and IXa for endothelial binding cites and thereby inhibit thrombosis formation.
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申请公布号 |
US4885277(A) |
申请公布日期 |
1989.12.05 |
申请号 |
US19870118316 |
申请日期 |
1987.11.06 |
申请人 |
OKLAHOMA MEDICAL RESEARCH FOUNDATION |
发明人 |
NAWROTH, PETER P.;STERN, DAVID M.;WILNER, GEORGE D. |
分类号 |
C07K14/52;A61K;A61K38/00;A61P7/02;C07K;C07K1/00;C07K7/06;C07K7/08;C07K14/485;C07K14/755;C12N9/64 |
主分类号 |
C07K14/52 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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