发明名称 Bactericidal quinoline carboxylic acid deriv. prepn.
摘要 6,8-Difluoro 1-(2-fluoro ethyl) 1,4-dihydro 4-oxo 7-(4-methyl 1-piperazinyl) quinoline 3-carboxylic acid and its salts, for use as anti-bacterial agents against gram-positive and gram-negative types, are made by hydrolysis of the corresp. nitrile in acid medium at 70-125 deg.C and isolation by conventional methods.
申请公布号 ES2010862(A6) 申请公布日期 1989.12.01
申请号 ES19890000502 申请日期 1989.02.13
申请人 INKE, S.A. 发明人 MONSERRAT FABA, EUSEBIO
分类号 A61K31/495;C07D403/04;(IPC1-7):C07D403/04 主分类号 A61K31/495
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