| 摘要 |
PURPOSE:To obtain a remarkable amount of the title compound produced and accumulated in a culture medium without adding expensive homoserine to the culture medium by culturing L-threonine producing bacterium belonging to the genus Providencia and having resistance to azaguanine. CONSTITUTION:A microorganism [e. g., Providencia rettgeri NK-878002 strain (FERH P-10009)] belonging to the genus Providencia, having resistance to 8- azaguanine and L-threonine producing ability is cultured to collect the aimed compound produced and accumulated in a culture medium. Furthermore, the culture is preferably carried out under aerobic conditions at pH4-9 and 20-40 deg.C. |
