| 摘要 |
NEW MATERIAL:Substance FR-900493 having the following physical and chemical properties. Appearance: while powder. Properties: amphoteric. Melting point: 157-160 deg.C (decomposition). Specific rotatory power: [alpha] =+27 deg.C (C=1.0, water). Molecular formula: C20H33M5O11. Elemental analysis (Z) calculated as C20H33N5O11. 2H2O: C 43.34, H 6.56, H 12.68. Molecular weight: GI-HS, m/z 520(M<+>+1). Solubility: soluble in water and insoluble in methanol, acetone, ethyl acetate and chloroform. Color reaction: positive in reaction with ninhydrin, iodine, etc., ]+ or - in Molish reaction and negative in reaction with ferric chloride and acetyl reagent. USE:An antimicrobial agent. PREPARATION:A strain [e.g., Bacillus cereus No2045 (FERM BP-1791). etc.] belonging to the genus Bacillus, capable of producing substance FR-900493, is cultivated in a nutritive medium preferably at 25-35 deg.C for 20-150 hours. |
