发明名称 |
3-Pyrrolidinylthio-1-azabicyclo(3,2,0) hept-2-ene-2-carboxylic acid compounds. |
摘要 |
<p>A compound of the formula : <CHEM> in which R<1> is carboxy or protected carboxy, R<2> is hydroxy(lower)alkyl or protected hydroxy(lower)alkyl, R<3> is hydrogen or lower alkyl, R<4> is unsaturated heterocyclic group which may be substituted by suitable substituent(s), R<5> is hydrogen, lower alkanimidoyl or imino-protective group, and A is lower alkylene, or pharmaceutically acceptable salts thereof, processes for their preparation and pharmaceutical compositions comprising them as an active ingredient in admixture with a pharmaceutically acceptable carrier or excipient.</p> |
申请公布号 |
EP0343499(A1) |
申请公布日期 |
1989.11.29 |
申请号 |
EP19890108896 |
申请日期 |
1989.05.18 |
申请人 |
FUJISAWA PHARMACEUTICAL CO., LTD. |
发明人 |
MURATA, MASAYOSHI;TSUTSUMI, HIDEO;MATSUDA, KEIJI;HATTORI, KOHJI;NAKAJIMA, TAKASHI |
分类号 |
C07D477/00;A61K31/397;A61K31/40;A61K31/41;A61K31/415;A61K31/435;A61K31/44;A61K31/495;A61K31/50;A61K31/505;A61P31/04;C07D477/20;C07D521/00 |
主分类号 |
C07D477/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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