发明名称 |
BETA-LACTAM COMPOUND, METHOD FOR PREPARING THE SAME, MEDICINAL COMPOSITION FOR BACTERIALLY INFECTIOUS DISEASE THERAPY CONTAINING THE SAME AND INTERMEDIATES FOR SYNTHESIS OF THE SAME |
摘要 |
<p>There are disclosed a beta -lactam compound represented by the formula (I): <CHEM> wherein R1 and R2 are independently a hydrogen atom or a lower alkyl group; M is a hydrogen atom, a protective group or an eliminatable group which is easily hydrolyzable in a human body; R' and R'' are independently a hydrogen atom or a protective group; A is a mercapto group substituted by a substituted or unsubstituted polycyclic nitrogen-containing heterocyclic ring or a group represented by the following formula (a): -OOCNR3R4 (a) where R3 and R4 are independently a hydrogen atom or a lower alkyl group, provided that R1 and R2 are both hydrogen atoms, both R3 and R4 being hydrogen atoms are excluded, or its pharmaceutically acceptable salt, and a method for preparing the same, medicinal composition for microbism therapy containing the same and intermediates for synthesis of the same.</p> |
申请公布号 |
EP0254495(A3) |
申请公布日期 |
1989.11.29 |
申请号 |
EP19870306330 |
申请日期 |
1987.07.17 |
申请人 |
SANKEI PHARMACEUTICAL COMPANY LIMITED;NIPPON PHARMACEUTICAL DEVELOPMENT INSTITUTE COMPANY LIMITED |
发明人 |
SHIMIZU, SHIGEO;TAKANO, HIROYUKI |
分类号 |
C07B;C07D;C07D277/38;C07D501/34;C07D519/00;(IPC1-7):C07D501/36;C07D501/18;A61K31/545 |
主分类号 |
C07B |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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