4-Piperidinealkanamine derivatives.

摘要

Compounds of general formula I (Z=O) are prepared by reacting 4-piperidinealkanamines with carboxylic acids or reactive derivatives thereof, such as the esters of lower aliphatic alcohols or acid halides. Compounds of general formula I (Z=CONH) are likewise obtained by means of the reaction between 4-piperidinealcanamines and isocyanates. <CHEM> The compounds of general formula I thus obtained, and the pharmaceutically acceptable salts thereof are of a great therapeutic utility, given their activity as specific antagonists of histamine H1 receptors.