Azacyclic carboxylic acid derivatives, their preparation and use.

摘要

Novel O-alkylated oximes of the general formula I <CHEM> wherein R<1> and R<2> are optionally substituted aromatic or heteroaromatic rings, R<3> is hydrogen or lower alkyl, R<4> is a nitrogen containing, substituted ring or an amino group carrying a substituted ring, and n and m independently are 0, 1 or 2, are potent inhibitors of GABA reuptake from the synaptic cleft.