| 摘要 |
Tetrahydrofuranyl and tetrahydrothienyl substituted ethers are provided having the structural formula <CHEM> wherein A is (CH2)2, CH = CH or a single bond, m is 1 to 5, B is a single bond or CH = CH, n is 1 to 4, X is O or <CHEM> wherein n min is 0, 1 or 2, R is H lower alkyl or alkali metal and R<1> is lower alkyl, arylalkyl, aryl, cycloalkyl, cycloalkylalkyl or lower alkenyl and including all stereoisomers thereof and Y is either oxygen or sulfur. The compounds are cardiovascular agents useful, for example, in the treatment of thrombolytic disease and as anti-inflammatory agents and analgesics. |
