Activation antigen

摘要

An essentially purified antigen comprising a protein present in the T-cells of Aotus trivirgatus having molecular weights of 140 KD and 105 KD under reducing conditions and 120 KD and 90 KD under non-reducing conditions, antibodies against this antigen, and a method of using these antibodies to activate T-cells. The antibodies are able to induce T-cell activation in synergy with phorbol myristate acetate alone and with antibody against the T 113 epitope of T 11 (CD2) antigen alone.