| 摘要 |
PURPOSE:To obtain a standard liquid for measurement of total bilirubin, direct- type bilirubin in human bodily fluid of special stability, by allowing co-existence of conjugation-type bulirubin and non-ion-type surface-active agent and long- period longevity. CONSTITUTION:To a conjugation-type bilirubin solution where in propionic acid residual radical is combined with glucuronic acid, taurine, etc., non-ion surface active agents of HLB 10-20, such as, polyethylene glycol setylether, polyethylene glycol nonylphenyl ether, etc. are added at a rate of 0.2-10W/V%. Further, when a reducing agent of glutathione, cystine, ascorbic acid is added at 0.0005- 0.02W/V%, stability is improved. The keeping quality lasts innthis state of solution, however, freeze drying of the solution result to elongated stability. The frozen product is melted again in distilled water when using. Thus, a standard liquid of excellent stability suited to diagnosis of hemolitic jaundice, obstructive jaundice. |
