发明名称 IMMUNOGENS AND BIOLOGICALLY ACTIVE PEPTIDES DERIVED FROM SHARED SEQUENCES FROM ANTIGENS AND ANTI-IDIOTYPIC ANTIBODIES OR ANTIBODIES SPECIFIC FOR CELLULAR RECEPTORS OF THE ANTIGENS
摘要 <p>A novel method of synthesizing immunogens is disclosed. First a shared sequence between an anti-receptor antibody for an external antigen and antigen itself is determined. The shared sequence is then used to construct peptides which may be used as immunogens. A method of providing agents for binding to cellular receptors is also disclosed. Such receptor binding agents are similarly constructed by determining a shared sequence between anti-receptor antibodies and an external antigen. The resulting products may be used as vaccines or as pharmaceuticals which are either directly active on the target cells, or indirectly active as the result of preventing receptor binding by the subject antigen.</p>
申请公布号 WO1989010939(A1) 申请公布日期 1989.11.16
申请号 US1989001815 申请日期 1989.04.28
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