发明名称 |
Process for the preparation of L-alpha-amino acid and d-alpha-amino acid amide |
摘要 |
The invention relates to a process for preparation of L- alpha -amino acid and D- alpha -amino acid amide from DL- alpha -amino-acid amide by contacting the DL- alpha -amino acid amide in an aqueous solution with an alpha -amino acid amidase containing preparation obtained from a culture of Pseudomonas putida in the presence of traces of bivalent metal ions as activator, characterized in that the aqueous solution also contains a potassium salt selected from the group consisting of potassium sulphate and potassium chloride. The invention further relates to a process for the preparation of L- alpha -amino acid and D- alpha - amino acid amide starting from the corresponding aldehyde, potassium cyanide and ammoniumsulphate, subsequent treatment with a ketone and potassiumhydroxide and finally subjecting to enzymatic hydrolysis with a preparation obtained from Pseudomonas putida.
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申请公布号 |
US4880737(A) |
申请公布日期 |
1989.11.14 |
申请号 |
US19850792006 |
申请日期 |
1985.10.28 |
申请人 |
STAMICARBON B.V. |
发明人 |
KERKHOFFS, PIETER L.;BOESTEN, WILHELMUS H. J. |
分类号 |
C12P41/00;C12N9/80;C12P13/04;C12R1/40 |
主分类号 |
C12P41/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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