发明名称 FREMGANGSMAATE FOR FREMSTILLING AV NYE KARBOKSYLSYREDERIVATER.
摘要 <p>3-Pyrrolidinylthio-1-azabicyclo(3.2.0)-hept-2-ene-2-carbocylic acid derivatives of the formula: <CHEM> in which R<1> is carboxy or protected carboxy, R<2> is hydroxy(lower)alkyl or protected hydroxy(lower)alkyl, R<3> is hydrogen or lower alkyl, R<4> is monohalo(lower)alkyl, mono- or di(lower)alkylamino(lower)alkyl, protected mono(lower)alkylamino(lower)alkyl, mono- or di(lower)alkylcarbamoyl(lower)alkyl, or protected or unprotected carboxy(lower)alkyl, R<5> is hydrogen, lower alkanimidoyl, lower cycloalkenyl which may have suitable substituent(s) or imino-protective group, and A is lower alkylene, or pharmaceutically acceptable salts thereof, processes for their preparation and pharmaceutical compositions comprising them as an active ingredient.</p>
申请公布号 NO891919(A) 申请公布日期 1989.11.13
申请号 NO19890001919 申请日期 1989.05.11
申请人 FUJISAWA PHARMACEUTICAL CO LTD 发明人 MURATA, MASAYOSHI;TSUTSUMI, HIDEO;MATSUDA, KEIJI;HATTORI, KOHJI;NAKAJIMA, TAKASHI
分类号 C07D477/00;A61K31/397;A61K31/40;A61P31/04;C07D207/12;C07D477/20;C07F7/18;(IPC1-7):C07D487/04 主分类号 C07D477/00
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