Novel physiologically active polypeptide and pharmaceutical composition.

摘要

This invention relates to a novel physiologically active polypeptide having antitumor activity obtained by improving human tumor necrosis factor, a DNA fragment encoding the polypeptide, a recombinant plasmid containing the DNA fragment, a recombinant microorganism cell transformed with the plasmid, a method of producing a novel physiologically active polypeptide using the microorganism cell, and a pharmaceutical composition comprising the polypeptide as an active ingredient.