发明名称 |
A DNA SEQUENCE ENCODING THE -i(MAS) ONCOGENE, POLYPEPTIDES ENCODED THEREFROM, AND DIAGNOSTIC AND OTHER METHODS BASED THEREON. |
摘要 |
<p>This invention provides a DNA sequence comprising an activated oncogene, said oncogene encoding a polypeptide capable of transforming NIH3T3 cells and of inducing a tumor when injected into nude mice, said DNA sequence having a nucleotide sequence substantially as shown in FIGS. 3A and 3B. The invention also concerns a polypeptide molecule encoded by an activated oncogene, said molecule having the properties of transforming NIH3T3 cells and of inducing a tumor when injected into nude mice and further said polypeptide having an amino acid sequence substantially as shown in FIGS. 3A and 3B. Finally, this invention provides a method for treating a tumor induced by an activated mas oncogene.</p> |
申请公布号 |
EP0272321(A4) |
申请公布日期 |
1989.11.07 |
申请号 |
EP19870905674 |
申请日期 |
1987.06.02 |
申请人 |
COLD SPRING HARBOR LABORATORIES |
发明人 |
YOUNG, DALLAN;WIGLER, MICHAEL, H.;FASANO, OTTAVIO |
分类号 |
G01N33/50;A61K38/00;A61K39/00;A61K39/395;C07H21/04;C07K14/00;C07K14/82;C07K16/00;C07K16/32;C12N15/09;C12P21/02;C12Q1/68;C12R1/91;G01N33/574 |
主分类号 |
G01N33/50 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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