| 发明名称 |
IMPROVED PROCESS FOR PREPARING 5,6-SUBSTITUTED 2,4-QUINAZOLINE DIAMINES |
| 摘要 |
An improved process for the preparation of 6-substituted-5-alkyl-2,4-quinazolinediamines, useful in the production of trimetrexate and similar antifolate agents, together with several novel intermediates are disclosed. |
| 申请公布号 |
PH23781(A) |
申请公布日期 |
1989.11.03 |
| 申请号 |
PH19470000355 |
申请日期 |
1987.07.15 |
| 申请人 |
WARNER-LAMBERT CO. |
发明人 |
ELLEN MYRA BERMAN;MARK JAMES SUTO |
| 分类号 |
C07D239/95;A61K;C07C255/00;C07C255/49;C07C255/51;C07C255/58;C07D;C07D239/00;C07D239/84;C07D239/94 |
主分类号 |
C07D239/95 |
| 代理机构 |
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代理人 |
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