发明名称 PAROMOMYCIN OR DERIVATIVES THEREOF FOR PARENTERAL TREATMENT OF HUMAN PARASITIC DISEASES
摘要 A compound of formula (I), wherein R1 is a hydroxy group or an amino group optionally substituted with a C1-C4 alkyl or phenyl-(C1-C4)alkyl group, R2 is hydrogen or a hydroxy group, R3 is hydrogen or chlorine, R4 is hydrogen or a hydroxy or amino group, R5 is hydrogen or a hydroxy group, and R6 is hydrogen or a hydroxy group, or a non-toxic acid addition salt thereof, is useful in the parenteral treatment of visceral leishmaniasis or malaria, and a synergistic composition comprising a compound of formula (I) or a non-toxic acid addition salt thereof and sodium stibogluconate is useful in the treatment of visceral leishmaniasis.
申请公布号 WO8910130(A2) 申请公布日期 1989.11.02
申请号 WO1989EP00461 申请日期 1989.04.26
申请人 FARMITALIA CARLO ERBA S.R.L. 发明人 DONNO, LUIGI;CASSINELLI, GIUSEPPE
分类号 A61K31/00;A61K31/70;A61K31/7028;A61K31/7034;A61K31/7036;A61K33/24;A61P33/00;A61P33/02;C07H15/232 主分类号 A61K31/00
代理机构 代理人
主权项
地址