Hepatitis A virus antigen.

摘要

A hepatitis A virus antigen comprising inactivated or attenuated hepatitis A virus particles is disclosed in the present application. The present antigen coprises both complete particles containing the hepatitis A virus RNA and immature empty particles free of the virus RNA. By using these two kinds of virus particles as materials for vaccines, the infection with hepatitis A can be prevented or treated. Moreover, the HAV antigen can be used as an immunogen for obtaining an anti-HAV antibody or immunoglobulin for imparting passive immunization to an objection animal.