发明名称 PAROMOMYCIN OR DERIVATIVES THEREOF FOR PARENTERAL TREATMENT OF HUMAN PARASITIC DISEASES
摘要 <p>A compound of formula (I), wherein R1 is a hydroxy group or an amino group optionally substituted with a C1-C4 alkyl or phenyl-(C1-C4)alkyl group, R2 is hydrogen or a hydroxy group, R3 is hydrogen or chlorine, R4 is hydrogen or a hydroxy or amino group, R5 is hydrogen or a hydroxy group, and R6 is hydrogen or a hydroxy group, or a non-toxic acid addition salt thereof, is useful in the parenteral treatment of visceral leishmaniasis or malaria, and a synergistic composition comprising a compound of formula (I) or a non-toxic acid addition salt thereof and sodium stibogluconate is useful in the treatment of visceral leishmaniasis.</p>
申请公布号 WO1989010130(P1) 申请公布日期 1989.11.02
申请号 EP1989000461 申请日期 1989.04.26
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