| 发明名称 |
MONOCLONAL ANTIBODIES TO TISSUE PLASMINOGEN ACTIVATOR (T-PA) WHICH PROLONG ITS FUNCTIONAL HALF-LIFE |
| 摘要 |
High-affinity murine monoclonal antibodies to t-PA were prepared which prolong the in vivo functional half-life of t-PA without decreasing its plasminogen-activator activity. |
| 申请公布号 |
AU3332389(A) |
申请公布日期 |
1989.11.02 |
| 申请号 |
AU19890033323 |
申请日期 |
1989.04.24 |
| 申请人 |
E.I. DU PONT DE NEMOURS AND COMPANY |
发明人 |
THOMAS MICHAEL REILLY;ANDREW TAK-CHAU CHIU;ROBERT MADARA KNABB |
| 分类号 |
A61K35/74;A61K38/00;A61K38/49;A61K39/395;A61P7/02;C07K16/40;C12P21/08;C12R1/91 |
主分类号 |
A61K35/74 |
| 代理机构 |
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代理人 |
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