| 摘要 |
<p>A therapeutic and prophylactic agent for peptic ulcers which contains as an active ingredient a compound of the general formula (I): <IMAGE> (I) wherein R1 represents hydrogen or =O; R2 represents hydrogen or -OR5; R3 represents hydrogen or -OR6; R4 represents -OR7 in the case of the absence of double bond; R5, R6 and R7 each represents hydrogen or an organic residue; X represents group (A): =C=CH-COR8 (A) or group (B): <IMAGE> (B) wherein R8 represents alkyl, and R9 and R10 each represents hydrogen or an organic residue; with the proviso that when X represents group (A), then R1 and R3 both represent hydrogen, R2 represents -OR5; R4 represents OR7 and the bond between the carbon atoms to which X is attached and the carbon atom to which R4 is attached is a single bond, and when X represents group (B), then R1 represents =O, R2 represents hydrogen, R3 represents -OR6 and the bond between the carbon atom to which X is attached and the carbon atom to which R4 is attached is a double bond, or a pharmaceutically acceptable salt thereof, or a compound of the general formula (II): <IMAGE> (II) wherein R11 represents hydrogen or an organic residue, and R12, R13 and R14 each represents an organic residue, or a pharmaceutically acceptable salt thereof. The compounds of the general formulae (I) and (II) can be derived from compounds contained in a hot water extract of cinnamon.</p> |
