发明名称 |
13-deoxy-23-imino derivatives of 13-deoxy C-076-aglycone compounds |
摘要 |
The present invention relates to novel 23-imino derivatives of C-076 wherein the C-076 compounds are not substituted at the 13-position. The C-076 compounds (collectively) are isolates from the fermentation broth of Streptomyces avermitilis. The precursor 23-oxo compounds are prepared by selectively oxidizing suitably protected 13-deoxy C-076 aglycone compounds by using oxidizing agents. Subsequently, the 23-oxo compounds are converted to the 23-imino compounds. These novel compounds have potent anthelmintic, insecticidal, ectoparasticidal, nematicidal and acaricidal activity. Compositions containing these 23-oxo and 23-imino derivatives of 13-deoxy C-076 aglycones also are described herein.
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申请公布号 |
US4877888(A) |
申请公布日期 |
1989.10.31 |
申请号 |
US19870088952 |
申请日期 |
1987.08.27 |
申请人 |
AMERICAN CYANAMID COMPANY |
发明人 |
ASATO, GORO;FRANCE, DONALD J. |
分类号 |
A01N43/90;A01N47/24;A01N47/34;A23K1/17;C07H19/01 |
主分类号 |
A01N43/90 |
代理机构 |
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地址 |
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