摘要 |
Compound, corresponding to the formula C8H17-(C 3BOND C-CH2)3-CH2CH2CH2COR (I) in which R is a C1-C8 lower alkoxy or C4-C6 cycloalkoxy group, substituted with one or more hydroxyl groups and/or interrupted by one or more hetero atoms chosen from oxygen and sulphur, an amino group of structure <IMAGE> in which R1 or R2, which may be identical or different, denote a hydrogen atom or a linear or branched C1-C8 lower alkyl radical, optionally interrupted by one or more hetero atoms chosen from oxygen, sulphur and nitrogen, this alkyl radical being able to be substituted with one or more hydroxyl groups, R1 and R2 not being able to denote hydrogen simultaneously, or alternatively R1 and R2 form, together with the nitrogen atom, a heterocyclic system optionally containing oxygen, sulphur or nitrogen as an additional hetero atom, one of the radicals R1 and R2 also being able to denote, when the other is a hydrogen atom, an aryl radical of formula (II): <IMAGE> (II) or alternatively a benzyl radical of formula (III): <IMAGE> (III) in which formulae R3 and R4, denote, independently of each other, a hydrogen atom, a C1-C4 alkyl radical, a hydroxyl group, a halogen atom or a carboxyl or trifluoromethyl group, the amine group also being able to originate from a sugar, and also the isomers and salts thereof which are pharmaceutically and cosmetically acceptable.
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申请人 |
CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES DITE C.I.R.D. |
发明人 |
SHROOT, BRAHAM;HENSBY, CHRISTOPHER;MAIGNAN, JEAN;LANG, GERARD;RESTLE, SERGE;COLIN, MICHEL |