摘要 |
<p>PURPOSE: To obtain a mixed live vaccine composed of a spontaneous erythrocyte agglutinating infectious bronchitis virus and other virus of fowl infectious disease and free from the problems of conventional mixed live vaccine. CONSTITUTION: This mixed live vaccine for immunizing a fowl against viral infectious diseases is composed of (A) an infectious bronchitis virus spontaneously agglutinating chicken erythrocyte, preferably Ma5 strain (ATCC VR2199) or an infectious bronchitis virus belonging to spontaneous erythrocyte- agglutinating strain originated from the Ma5 strain and (B) at least one kind of virus of infectious disease of fowl, e.g. Newcastle disease virus, epidemic pustule virus, egg drop syndrome virus, Marek's disease virus, fowl herpes virus, leukemia virus, fowl adenovirus, etc. The live vaccine is administered to young fowl of preferably from one day old to the egg-laying stage (about 18 week old) by intramuscular injection, hypodermic injection or intraovular injection or in the form of eye drop, nasal drop, addition to drink water or spray.</p> |