| 摘要 |
PURPOSE: To obtain a pharmaceutical preparation containing a calcium antagonistic agent and a hypolipidemic agent, effective for improving the flowability of blood by the synergistic action and useful for the treatment of coronary vascular cardiopathy. CONSTITUTION: This combined preparation contains (A) a calcium antagonistic agent, preferably verapamil or gallopamil and (B) a hypolipidemic agent, preferably bezafibrate, clofibrate, etofibrate or fenofibrate at an A:B ratio of 10:1 to 1:10 (1:2 to 2:1 in the case of a combination of verapamil and fenofibrate). Both components may be used as separate preparations and applied simultaneously or interposing an interval. The preparation is useful for the treatment and prevention of symptoms caused by the myocardial blood flow disorder in coronary heart diseases, e.g. all kinds of stenocardia, post-treatment of myocardial infarction and the use before and after the balloon expansion method and bypass operation. |
