| 摘要 |
NEW MATERIAL:An alkylenediamine derivative expressed by the formula (R<1> is H, aliphatic hydrocarbon, alicyclic hydrocarbon, aryl, aryl-substituted alkyl, etc.; Y is O or S; R<2> is aliphatic hydrocarbon, aryl-substituted alkyl, etc.; R<3>-R<5> are H, alkyl, alkoxy, acyl, acyloxy, aryl, aralkyl OH, halogen, nitrile, etc.; p is 2-10; q is 4-7) or salt thereof. EXAMPLE:N-(2-Hydroxy-2-phenylethyl)-N-(3-piperidinopropyl)heptan-amide. USE:A glutamic acid blocker, remedy for neuropathy and agricultural chemicals (capable of blocking neuromuscular junctions of insects and diminishing activity thereof). PREPARATION:For example, 2-amino-1-phenylethane-1-ol is obtained from alpha- aminoacetophenone and passed through N-(2-hydroxy-2-phenylethyl)-N-(3- piperidinopropy)heptanamide to afford the exemplified compound. |
