发明名称 LAK CELL CYTOTOXIN
摘要 The present invention is directed to a unique group of cytokines produced by the stimulation of mammalian peripheral blood mononuclear cells with interleukin-2. More particularly, the present invention is directed to lymphokine activated killer cell cytotoxin (LCC), and to methods of production thereof, having unique cytotoxic and cytostatic activity against tumor cells. The present invention also contemplates a pharmaceutical composition comprising said cytokine and a pharmaceutically acceptable carrier useful in the treatment and prophylaxis of cancer and infectious diseases.
申请公布号 WO8909831(A1) 申请公布日期 1989.10.19
申请号 WO1989US01387 申请日期 1989.04.05
申请人 RESEARCH CORPORATION TECHNOLOGIES, INC. 发明人 HERSH, EVAN, M.;SCUDERI, PHILIP, JR.;GRIMES, WILLIAM;SALMON, SYDNEY, E.
分类号 C12N15/09;A61K38/00;A61P35/00;C07K14/005;C07K14/195;C07K14/52;C07K16/00;C07K16/24;C12P21/00;C12R1/91;(IPC1-7):C12P21/00 主分类号 C12N15/09
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