发明名称 RUTHENIUM COMPOUNDS HAVING A TUMOR INHIBITING ACTIVITY
摘要 PCT No. PCT/EP85/00369 Sec. 371 Date Mar. 21, 1986 Sec. 102(e) Date Mar. 21, 1986 PCT Filed Jul. 24, 1985 PCT Pub. No. WO86/00905 PCT Pub. Date Feb. 13, 1986.A compound of the general formula I (BHn)m[RuX3+nm-q-r(OH)r(BHp)3-nm+q]1+p+q I wherein B denotes a mononuclear or polynuclear basic heterocyclic radical containing one or more nitrogen atoms, X denotes chlorine or bromine, m denotes 1 or 2, n denotes 1 or 2, the sum of n and m being not greater than 3, p denotes 0 or 1, but not 1 if n is 1, q denotes 0 or 1, but not 1 if p is 1 and r denotes 0 or 1, show an antitumoral activity and are therefore suitable as a chemotherapeutic for the treatment of cancers.
申请公布号 DE3572981(D1) 申请公布日期 1989.10.19
申请号 DE19853572981 申请日期 1985.07.24
申请人 ASTA PHARMA AG 发明人 KELLER, HEIMO, J.;KEPPLER, BERNHARD
分类号 C07F15/00;A61K33/00;A61K33/24;A61P35/00;(IPC1-7):C07F15/00;A61K31/28 主分类号 C07F15/00
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