发明名称 |
N-HETEROCYCLIC PROPYLIDENE-1,1-BISPHOSPHONIC ACIDS, THEIR PRODUCTION AND A PHARMACEUTICAL COMPOSITION |
摘要 |
The present invention relates to compounds of formula (I) in which R1-R8 can be the same or different and stand for hydrogen or a straight or branched aliphatic C1-C10 hydrocarbon radical. In addition, R3 when taken together with either R1 or R5 can form a saturated aliphatic 5-, 6- or 7-membered ring, which may be substituted with one or more C1-C4-alkyl radicals. The present compounds are effective e.g. in drugs influencing calcium metabolism. |
申请公布号 |
WO8909775(A1) |
申请公布日期 |
1989.10.19 |
申请号 |
WO1989DK00071 |
申请日期 |
1989.03.29 |
申请人 |
LEO PHARMACEUTICAL PRODUCTS LTD. A/S (LOEVENS KEMIS |
发明人 |
BINDERUP, ERNST, TORNDAL;LIISBERG, SVEN |
分类号 |
A61K31/675;A61P43/00;C07F9/572;(IPC1-7):C07F9/56;C07F9/65 |
主分类号 |
A61K31/675 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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