摘要 |
The present invention relates to a process for the preparation of compounds of the general formula I <IMAGE> in which either R<1> is H or Cl and R<2> is NH2 or R<1> is NH2 and R<2> is Cl, by catalytic hydrogenation of a compound of the general formula II <IMAGE> in which either R<3> is H or Cl and R<4> is NO2 or R<3> is NO2 and R<4> is Cl, in an organic solvent, the process being characterised in that the catalyst used is a sulphited platinum-on-carbon catalyst, the hydrogenation is carried out at temperatures from 20 to 100@C and, after the reaction has ended, the reaction mixture is heated to the boiling point of the solvent to isolate the product.
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申请人 |
HOECHST AG, 6230 FRANKFURT, DE |
发明人 |
KOCH, VOLKER, DR., 6233 KELKHEIM, DE;BERZEL, HUBERT, 6384 SCHMITTEN, DE;FISCHER, HARTMUT, DR., 6238 HOFHEIM, DE |