发明名称 |
Tetrahydroisoquinolines and tetrahydrobenzazepines and a process for the preparation thereof. |
摘要 |
<p>The present invention relates to novel bicyclic amine compound and a pharmaceutically acceptable salt thereof, which is an N-methyl-D-aspartate (an excitatory amino acid) receptor antagonist and useful as an anticonvulsant and a drug for treatment of the delayed neuronal death induced, for instance, by cerebral ischemia, for example, in case of cardiac arrest, to a process for the preparation thereof, to a pharmaceutical composition comprising the same, and to a use of the same as a medicament in treatment of convulsion and delayed neuronal death in human being or animal.</p> |
申请公布号 |
EP0336228(A1) |
申请公布日期 |
1989.10.11 |
申请号 |
EP19890105218 |
申请日期 |
1989.03.23 |
申请人 |
FUJISAWA PHARMACEUTICAL CO., LTD. |
发明人 |
TAKASUGI, HISASHI;KUNO, ATSUSHI;OHKUBO, MITSURU |
分类号 |
A61K31/47;A61K31/472;A61K31/55;A61P25/00;A61P25/08;C07D217/02;C07D217/04;C07D217/06;C07D217/10;C07D217/14;C07D217/16;C07D223/16;C07D401/06;C07D405/04;C07D409/04 |
主分类号 |
A61K31/47 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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