| 发明名称 |
Polypeptides stabilized by covalent hydrogen bond replacements. |
| 摘要 |
<p>Polypeptides are restricted to particular conformations in solution by replacing one or more hydrogen bonds with covalent hydrogen bond mimics of class 1 or class 2: <CHEM> The polypeptides thus stabilized are capable of greater biological activity.</p> |
| 申请公布号 |
EP0336779(A2) |
申请公布日期 |
1989.10.11 |
| 申请号 |
EP19890303469 |
申请日期 |
1989.04.07 |
| 申请人 |
SCRIPPS CLINIC AND RESEARCH FOUNDATION |
发明人 |
SATTERTHWAIT, ARNOLD C., JR.;ARRHENIUS, THOMAS;CHIANG, LIN-CHANG |
| 分类号 |
C07K1/00;C07K1/02;C07K1/04;C07K1/113;C07K5/06;C07K5/08;C07K7/06;C07K7/23;C07K14/00;C07K14/52;C07K14/555;C07K14/56;C07K14/575;C07K14/61;C07K14/655 |
主分类号 |
C07K1/00 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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