摘要 |
<p>The invention provides a selective process for preparing a 2,4- or 3,6-di-substituted phenol compound which comprises reacting an olefin compound of the formula: <CHEM> wherein R<1> is hydrogen, halogen, alkyl, halogen substituted-alkyl, aryl, halogen substituted-aryl or alkyl substituted-aryl; and R<2>, R<3> and R<4> are the same or different and each is hydrogen, halogen, alkyl, halogen substituted-alkyl or aralkyl; with a phenol compound of the formula: <CHEM> wherein R<5> is hydrogen, hydroxy, halogen, alkyl, halogen substituted-alkyl, alkoxy or -C(R<6>)(R<7>)CH(R<8>)(R<9>) (wherein R<6> is hydrogen, halogen, alkyl, halogen substituted-alkyl, aryl, halogen substituted-aryl or alkyl substituted-aryl; and R<7>, R<8> and R<9> are the same or different and each is hydrogen, halogen, alkyl, halogen substituted-alkyl or aralkyl), in the presence of a phosphorus compound and a carboxylic acid compound as catalysts.</p> |