发明名称 Tricyclic aromatic compounds
摘要 The present invention relates to compounds of formula I <IMAGE> (I) or a salt, ester or amide thereof; wherein R1 is -CH2-CH2-, CH2-O- or -O-CH2-; R2 and R3 are the same or different and are each hydrogen, C1-4 alkyl or taken together with the nitrogen comprise a nitrogen-containing heterocyclic ring having four to six ring members; R4 is a single bond or a C1-7 bivalent aliphatic hydrocarbon group and may be joined to the aromatic ring system at the 2,3,8 or 9 positions; n is 0 to 3, and their use as anithistamine and antiasthma agents.
申请公布号 US4871865(A) 申请公布日期 1989.10.03
申请号 US19860894306 申请日期 1986.08.07
申请人 BURROUGHS WELLCOME CO. 发明人 LEVER, JR., O. WILLIAM;LEIGHTON, HARRY J.
分类号 C07C59/86;A61K31/00;A61K31/335;A61P11/00;A61P37/08;A61P43/00;C07C51/00;C07C65/36;C07C67/00;C07C229/34;C07C229/38;C07C231/00;C07C231/12;C07C237/20;C07C237/30;C07C253/00;C07C255/42;C07C255/58;C07D313/12;C07D313/14 主分类号 C07C59/86
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