摘要 |
The transdermal therapeutic system is used for the combined administration of oestrogens and gestagens. The therapeutic system consists of
(1) a covering layer which is closed and impermeable to the constituents of the active agent formulation,
(2) a reservoir containing essential constituents of the active agent formulation and, if desired, a membrane,
(3) an adhesive layer and
(4) a protective layer, which can be pulled off, on the adhesive layer.
<??>The system contains an oestrogen derivative in combination with a synthetic gestagen and an agent which increases percutaneous absorption. |