| 发明名称 |
2-Hydroxy-3-aryloxy-propylamine derivatives having cardiovascular activity. |
| 摘要 |
<p>Compounds of the formula <CHEM> wherein Ar, R, R1 , R2, R3, R4, X and n have the meanings mentioned in the description, processes and intermediates for their preparation, pharmaceutical compositions which contain them and their use in therapy in the treatment of cardiovascular diseases.</p> |
| 申请公布号 |
EP0333938(A1) |
申请公布日期 |
1989.09.27 |
| 申请号 |
EP19880202681 |
申请日期 |
1988.11.24 |
| 申请人 |
SIMES, SOCIETA ITALIANA MEDICINALI E SINTETICI, S.P.A. |
发明人 |
CASAGRANDE, CESARE;SANTANGELO, FRANCESCO;CALABI, MARIA LUISA |
| 分类号 |
A61K31/34;A61K31/135;A61K31/165;A61K31/275;A61K31/33;A61K31/343;A61K31/40;A61K31/403;A61K31/4035;A61K31/41;A61K31/433;A61P9/00;A61P9/10;C07C217/32;A61P9/12;A61P25/02;C07C211/27;C07C217/34;C07C231/00;C07C235/34;C07C235/46;C07C237/06;C07C237/08;C07C255/54;C07C317/28;C07C323/20;C07C323/21;C07C323/30;C07C323/35;C07C323/41;C07D209/08;C07D209/48;C07D209/88;C07D213/85;C07D215/22;C07D215/227;C07D285/10;C07D285/14;C07D307/83;C07D521/00 |
主分类号 |
A61K31/34 |
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