ELECTROPHORETIC GEL FROM CROSSLINKED AND POLYMERIZED MONOMERS WITH POROSITY GRADIENT

摘要

PROCESS FOR PREPARATION OF ELECTROPHORESIS GEL MATERIAL A porous electrophoretic gel product is disclosed, comprising a water-swelled porous polymer matrix, formed polymerized and cross-linked monomers and a photoinitiator, which defines a volume, the product characterized by having a constant atomic composition over its volume, being stable, having a controlled, electrophoretic resolving capacity that is reproducible from gel to gel for the electrophoretic separation of charged macromolecular substances, having length, width and thickness dimensions, and having a porosity gradient along one of the length and width dimensions and uniform porosity along the thickness dimension which dimension is relatively thin. Photoinitiated polymerized gels afford the desired advantages of being ultra thin and having a high electrophoretic resolution with programmable porosity profiles.