| 发明名称 |
ANTIBODY-METAL ION COMPLEXES |
| 摘要 |
<p>This invention relates to antibody-metal ion complexes having a metal ion coordinately bound to a compatible chelator covalently bound to an antibody or antibody fragment. Also described are methods for intermediates in the preparation of antibody-metal ion complexes. Therapeutic and in vitro and in vivo diagnostic methods utilizing such antibody-metal ion complexes are described.</p> |
| 申请公布号 |
CA1260827(A) |
申请公布日期 |
1989.09.26 |
| 申请号 |
CA19850488912 |
申请日期 |
1985.08.16 |
| 申请人 |
CYTOGEN CORPORATION |
发明人 |
SIEGEL, RICHARD C.;LEE, CHYI;ALVAREZ, VERNON L.;RODWELL, JOHN D.;MCKEARN, THOMAS J.;GOERS, JOHN W. F. |
| 分类号 |
A61K51/00;A61K39/00;A61K39/395;A61K49/08;A61K51/10;C07K1/113;C07K14/00;C07K14/705;C07K16/00;C12P21/00;C12P21/08;G01N33/532;G01N33/534;G01N33/536;G01N33/577;(IPC1-7):G01N33/534;A61K49/02;A61K43/00 |
主分类号 |
A61K51/00 |
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