ANTIKOERPER, VERFAHREN ZU IHRER HERSTELLUNG, OLIGOSACCHARID-HAPTENE UND KLONE ZUR ERZEUGUNG DER ANTIKOERPER SOWIE VERWENDUNG DER ANTIKOERPER ZUR DIAGNOSE UND THERAPIE VON TUMOREN

摘要

Antibodies, specific for N-glycane structures of cell membrane surfaces and which, in an immunoassay, for example RIA and ELISA assay, or microtiter plates, exhibit a positive reaction to antigen oligosaccharides with structural elements of chitobiose and mannose trisaccharides, comprise structural elements of formula (I), wherein GN denotes N-acetylglucosamine and M denotes mannose, and the mannose residues are linked to each other through 1,3- and/or 1,6-glycosidic linkages.