| 发明名称 |
NOVEL MODIFIED NAD-DEPENDENT DEHYDROGENASES AND PROCESS FOR THEIR PRODUCTION |
| 摘要 |
Novel NAD-dependent dehydrogenases are provided which catalyse the reaction malate <SIGN> oxaloacetate. The enzymes may be further characterised by a low dependence upon the presence of fractose-1,6-biphosphate as activator. The novel enzymes may be desired from wild type enzymes, for example the lactate dehydrogenase of B. stearothermophilus by site-directed mutagenisis. |
| 申请公布号 |
WO8908707(A1) |
申请公布日期 |
1989.09.21 |
| 申请号 |
WO1989GB00279 |
申请日期 |
1989.03.16 |
| 申请人 |
THE UNIVERSITY OF BRISTOL;PUBLIC HEALTH LABORATORY SERVICE BOARD |
发明人 |
HOLBROOK, J., JOHN;CLARKE, ANTHONY, R.;ATKINSON, ANTHONY |
| 分类号 |
C12N15/09;C12N9/04;C12N15/53;C12R1/07;(IPC1-7):C12N15/00 |
主分类号 |
C12N15/09 |
| 代理机构 |
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