A PROCESS FOR THE PREPARATION OF THIAMPHENICOL GLYCINATE ACETYLCYSTEINATE

摘要

1,264,935. Process for thiamphenicol glycinate acetylcysteinate. ZAMBON S.p.A. 1 June, 1970 [7 June, 1969], No. 26257/70. Heading C2C. The therapeutic, title compound (I) is prepared by reacting thiamphenicol glycinate hydrochloride with dicyclohexylamine in a solvent, e.g. dimethylformamide, removing precipitated dicyclohexylammonium chloride from the reaction system, adding acetylcysteine to the residual solution and precipitating I, e.g. by adding chloroform or diethyl ether.