| 摘要 |
<p>A kit for preparing a fat emulsion of a drug of the type which must be prepared immediately before use, consists of two separate components which are mixed when required; (1) a fat emulsion, pref. contg. 0.1-50% (w/v) oil (such as soybean, cotton, safflower, corn or olive oil, an intermediate-chain fatty acid triglyceride, triacetin or eicosapentanoic acid); 1-50 pts. by wt. (per 100 pts.oil) of an emulsifier (such as lecithin, phosphatide, hydrogenated lecithin or a nonionic surfactant) and the balance water. The mean globule diameter in the emulsion is pref. below 1 micro m. (2) a drug, together with either (a) one or more solvents (water, a liquid polyalkylene glycol, liquid alkylethanolamine or liq. polyhydric alcohol. The pref. solvents are polyethylene glycol of mol. wt. below 800, polypropylene glycol or distilled water), or (b) an excipient such as a sugar and/or aminoacid.</p> |
