| 发明名称 |
INHIBITION OF HTLV-III BY EXOGENOUS OLIGONUCLEOTIDES |
| 摘要 |
Inhibition of HTLV-III by administration of a modified oligonucleotide complementary to highly conserved regions of the HTLV-III genome necessary for HTLV-III replication and/or gene expression is described, as are oligodeoxynucleotide sequences which are complementary to those regions, and methods of inhibiting HTLV-III replication and gene expression. |
| 申请公布号 |
WO8908146(A1) |
申请公布日期 |
1989.09.08 |
| 申请号 |
WO1989US00752 |
申请日期 |
1989.02.24 |
| 申请人 |
WORCESTER FOUNDATION FOR EXPERIMENTAL BIOLOGY |
发明人 |
GOODCHILD, JOHN;ZAMECNIK, PAUL, C.;AGRAWAL, SUDHIR |
| 分类号 |
G01N33/569;A61K31/70;A61K48/00;A61P31/12;C07H21/00;C12N15/09;C12N15/113;C12Q1/70;C12R1/92;G01N33/574;(IPC1-7):C12N15/00 |
主分类号 |
G01N33/569 |
| 代理机构 |
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